1191. Comparison of High Touch Surface Bioburden Associated with the Use of Disinfectants With and Without Continuously Active Disinfection Properties in Ambulatory Care Settings

Abstract Background Microbial contamination of high-touch surfaces (HTS) in health care settings contributes to pathogen transmission. HTS quickly become re-contaminated after disinfection. A quaternary ammonium (QA) and isopropyl alcohol (IPA)-based disinfectant (Sani-24®) with reported continuously active disinfection (CAD) properties for up 24 hours has been associated reduced microbial buildup on over time vitro studies inpatient healthcare settings. The performance this product ambulatory not reported. Methods bioburden use QA-IPA CAD was compared that a without (Super Sani-Cloth®) an urgent center (UCC) outpatient clinic (OPC). Surfaces/rooms were assigned 1:1 the disinfectants. Study team used pre-saturated wipes disinfect designated (stretcher/exam table, stretcher rail, armrest, doorknob, counter, light switch) at beginning each sampling period. In UCC, unit staff performed subsequent per routine protocols. OPC, study-assigned between patients. sampled 0, 4-6, 8-12, using Eswabs soaked neutralizing broth. burden quantified 48 incubation. Average CFU/cm² T-tests proportion samples < 2.5 CFU/cm², microbiologic standard environmental surfaces, by chi-square test. Results 66 UCC (33 disinfectant) 70 OPC (35 included. There no statistically significant differences average individual (Figure 1) or all combined also 2) Conclusion No observed following products CAD. These findings differ from those other settings, perhaps due frequent disinfection, less extensive recontamination, Hawthorne effect these Further study is warranted. Disclosures Harjot K. Singh, MD, clinical options: Advisor/Consultant|MJSciences/HCP Live: Advisor/Consultant|NYC Health Hospitals: Advisor/Consultant Lars Westblade, PhD, Accelerate Diagnostics, Inc.: Grant/Research Support|BioFire LLC: Support|Hardy Diagnostics: Support|Roche Molecular Systems, Advisor/Consultant|Roche Support|Shionogi, Advisor/Consultant|Talis Biomedical: Advisor/Consultant.